HIV Drug-Disease Matrix

June 2, 2010

Several years ago, graduate students at MIT’s PDOS research group attended the 9th World Multi-Conference of Systemics, Cybernetics, and Informatics.  Although their research paper Rooter: A Methodology for the Typical Unification of Access Points and Redundancy was accepted, their submission was nothing more than a randomly generated set of incomprehensible words organized to sound like legitimate science to challenge low submission standards for academic content.  (Readers can generate their own scientific papers here.)  

Although their harmless prank exposed scientific corruption, the pharmaceutical industry routinely produces similar gibberish to confuse their audience.  Like the 19th century salesmen who rode into town hawking cocaine and opiates as elixirs, their pharmaceutical progeny continues to market disease and deadly or highly addictive cures that kill or injure millions of Americans every year.

Since infectious disease became statistically insignificant by 1955, the NIH and CDC have wasted billions of tax dollars convincing Americans that they’ll die without medications that cause disease and kill

But how are we supposed to know?  Whether we read this advertisement or label information, we end up trusting clinicians who are paid to push drugs that kill

GlaxoSmithKline:

Zidovudine has been associated with hematologic toxicity including neutropenia, anemia… Prolonged use has been associated with symptomatic myopathy… Lactic acidosis and severe hepatomegaly with steatosis, including fatal cases, have been reported with the use of nucleoside analogues… Suspend treatment if clinical or laboratory findings suggestive of lactic acidosis or pronounced hepatotoxicity occur…

That doesn’t sound too bad, but what does it mean?  Plain English:

Zidovudine (and other AIDS drugs) causes liver, kidney and immune diseases.  Healthy and unhealthy people who take HIV drugs will eventually acquire cancer or an immune deficiency syndrome that will sicken or kill them.

All 4 classes of antiretrovirals (ARVs) and all 19 Food and Drug Administration–approved ARVs have been directly or indirectly associated with life-threatening events and death.  (Reisler et al, 2003).

Virological response after starting HAART improved over calendar years, but such improvement has not translated into a decrease in mortality.  (Lancet 2006)

OMSJ’s (Plain-English) HIV Drug Guide

To make sense of HIV drugs and packaging material, OMSJ has produced this guide that translates packaging material into easily understood warnings.  If you take HIV drugs now, click on drugs and the diseases they cause.  If you don’t see a drug, contact OMSJ and we’ll add it.

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