THe following anti-HIV drugs are known to
cause
“HEART ABNORMALITIES”
|
|
The
anti-HIV drugs are quite toxic to the mitochondria of cells, causing diseases
that affect virtually all tissues and organs: mitochondrial myopathy,
cardiomyopathy, neuropathy, lactic acidosis, pancreas failure, diabetes, liver failure
and bone marrow failure.
Organ
manifestations of mitochondrial toxicity. The question
marks
signify manifestations being debated as of 2007.
Bewildering
diversity of diseases caused by mitochondrial toxicity of anti-HIV drugs
Many
appear in the black box warning labels of the anti-HIV drugs:
|
Disorder |
Manifestations |
|
Neurological Neuromuscular Heart Endocrine Gastrointestinal Kidney Blood Psychiatric General |
Peripheral neuropathy, encephalopathy, dementia, seizures,
stroke Muscle
weakness, exercise intolerance Weak
heart, conduction disorders Diabetes
mellitus, lipid elevation Colonic
pseudo-obstruction, exocrine pancreas dysfunction, pancreatitis,
hepatomegaly, steatosis, liver failure, lactic acidosis Non-selective
proximal tubular dysfunction with acidic blood, phosphaturia and glucosuria,
glomerulopathy Anemia,
thrombocytopenia, pancytopenia Depression Multiple
systemic lipomas, fatigue |
HEART
ABNORMALITIES were described shortly
after the introduction of anti-HIV drugs. A 26% increase in the incidence of
heart attacks was found with each year of anti-HIV drug use.
